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What is Epzicom?
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Epzicom is a combination of two HIV medications in one tablet. The two medications
combined are Ziagen and Epivir. This was done to decrease the number of
pills that a person has to take to treat HIV infection. Epzicom, like all
HIV medications, should be taken in combination with other HIV medications
as prescribed.
How does Epzicom work?
Epzicom interferes with a very important HIV specific enzyme, which prevents
the ability of HIV virus to replicate. When Epzicom is taken in combination
with other HIV medications the goal is to prevent the virus from further
weakening the immune system. If Epzicom is working you should expect to
see an increase in T-cells (CD4 immune cells) and decrease in HIV viral
load.
How should Epzicom be taken?
Epzicom can be taken with or without food. Epzicom should be taken once
a day.
It is very important to try not to miss or skip any doses. The fewer doses a person skips, the fewer opportunities the virus has to develop resistance to HIV medications.
What does Epzicom look like?
Epzicom is an orange oval shaped tablet that has GS FC2 printed on one side.
What are the potential side effects of Epzicom?
Epivir is very well tolerated and has few side effects.
Ziagen can cause a hypersensitivity (allergic) reaction in approximately 5% of the people who take this medication. If you have a known allergy to Ziagen or abacavir then DO NOT take Epzicom. The symptoms of this reaction are describes as if suffering from a “flu-like” illness. Therefore, if you experience fever, nausea/vomiting, fatigue/weakness, muscle or joint pain, diarrhea, rash, or respiratory symptoms such as cough or sore throat, then contact your medical provider before stopping Epzicom. If the decision is made to stop Epzicom, then the allergic symptoms typically resolve in 48-72 hours. The allergic reaction is most likely to occur within the first 4-6 weeks after starting Epzicom.
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