Agenerase belongs to a class of drugs called protease inhibitors which are used to treat HIV infection. In order to treat HIV effectively, Agenerase MUST be taken in combination with other HIV medications as prescribed.

How does Agenerase work ?
Agenerase interferes with a particular HIV specific enzyme. This enzyme is important because it allows for the production of new HIV viruses which can infect more T-cells (CD4 immune cells). When Agenerase is taken in combination with other HIV medications the goal is to prevent the virus from further weakening the immune system. If Agenerase is effective then you should expect to see an increase in T-cells and decrease in HIV viral load. Not everybody responds to Agenerase, however you can improve the chance that Agenerase will work by taking ALL your medications everyday.

What does Agenerase look like ?
Agenerase is an white/cream colored 150 mg soft-gel capsule with the letters GX-CC2 printed on one side.

How should Agenerase be taken ?
There is more then one dose for Agenerase. Some people may take eight 150 mg capsules twice a day (16 capsules a day). More often medical providers are prescribing a lower dose of Agenerase in combination with another protease inhibitor (Norvir). For example, Agenerase is often used in combination with ritonavir (Norvir) at a dose of 600 mg Agenerase (4 capsules) + 100 mg ritonavir (1 capsule) twice a day. Agenerase can be taken with or without food.

It is very important to try not to miss or skip any doses. The fewer doses a person skips the fewer opportunities the HIV virus has to develop resistance to the medication.

Who should NOT take Agenerase ?
Children under 4 years old should NOT take Agenerase.

What are potential side effects of Agenerase ?
Agenerase can cause nausea, diarrhea, fatigue, and rash. Tell your medical provider immediately if a rash develops while taking Agenerase. If you are allergic to sulfa drugs, such as Bactrim or dapsone, then you need to tell your medical provider before starting Agenerase.

Are there potential drug interactions with Agenerase ?
Yes !! Agenerase can interact with other medications, therefore it is important to tell your medical provider and pharmacist about any other medications you are also taking with Agenerase. Agenerase capsules contain large amounts of vitamin E, therefore do not take vitamin E supplements while taking Agenerase.